Helmholtz Zentrum Muenchen

As German Research Center for Environmental Health, Helmholtz Zentrum München seeks to develop personalized medicine for the prevention and therapy of diabetes mellitus.

The Diabetes Research Department at Helmholtz Zentrum München understands diabetes to be a systemic disease in which both genetic and environmental factors – in particular lifestyle – play a role. In its endeavor to develop new approaches to therapy, prevention and diagnosis, the research center cooperates closely with the two Munich universities. Emphasis is placed on an integrated research focus with close collaboration between basic and clinical research. A diabetes research matrix ensures that the existing expertise is optimally harnessed and disseminated in three research areas: translational research and clinical projects, molecular mechanisms of diabetes development, and systems biology and modeling.

Speaker:

• Prof. Dr. Martin Hrabě de Angelis

Institutes and associated groups:

• Institute of Diabetes Research: Prof. Dr. Ziegler, Dr. Achenbach
• Institute of Diabetes and Obesity: Prof. Dr. Tschöp, Dr. Pfluger
• Institute of Diabetes and Regeneration Research: Prof. Dr. Lickert, Dr. Burtscher
• Institute of Experimental Genetics: Prof. Hrabé de Angelis, PD Dr. Beckers, Dr. Neschen, Dr. Hofmann
• Clinical Cooperation Group Nutrigenomics und Typ-2-Diabetes mellitus, TUM: Prof. Dr. Hans Hauner
• Clinical Cooperation Group Prediction and Subclassification of Typ-2-Diabetes mellitus, LMU: Prof. Dr. Seissler
• Institute of Epidemiology I: Dr. Joachim Heinrich (komm.)
• Institute of Epidemiology II: Prof. Dr. Peters
• Research Unit  Molecular Epidemiology: Prof. Peters (komm.), Dr. Grallert, Dr. Wang-Sattler
• Institute of Genetic Epidemiology: Prof. Strauch
• Institut of Health Economics and Health Care Management: Prof. Dr. Leidl, Prof. Dr. Holle
• Genom Analysis Center: Prof. Dr. Adamski
• Institute of Human Genetics: Prof. Dr. Meitinger, Dr. Strom
• Institute of Bioinformatics and System Biology: Prof. Dr. Mewes
• Research Unit Protein Science: Prof. Dr. Ueffing
• Institute of Ecological Chemistry: Prof. Dr. Zimmermann (komm.)
• Research Unit Microbe-Plant-Interactions: Prof. Dr. Hartmann
• Research Unit Analytical BioGeoChemistry: Prof. Dr. Schmitt-Kopplin
• Co-operation partners at the TUM: Prof. Dr. Klingenspor, Prof. Dr. Daniel

Contribution to the DZD research program:

• Establishment and characterization of relevant mouse models
• Development of a vaccine strategy for type 1 diabetics
• Identification of early predictive metabolic markers, personalized type 2 diabetes risk prognosis
• Differentiation of embryonic stem cells into insulin-secreting cells