University Clinic C.G.C. Dresden / Paul Langerhans Institute

The program of the institute includes research into the pathophysiology of diabetes mellitus type 1 and type 2. The main focus is on the mechanisms which cause the destruction and/or limited function of pancreatic beta cells and insufficient insulin secretion.

Speaker:

• Prof. Dr. Michele Solimena

Associated groups:

• Prof. Dr. Bonifacio
• Prof. Dr. Bornstein
• Prof. Dr. Saeger
• Prof. Dr. Brendel
• Prof. Dr. Chavakis
• Prof. Dr. Schwarz
• Dr. Kretschmer
• Dr. Ludwig
• Dr. Speier

Contribution to the DZD research program:

• Transplantation of human pancreatic islets
• Molecular mechanisms and systems biology of insulin granules
• Identification of new therapy goals for increasing beta-cell mass and insulin secretion
• Functional beta-cell imaging
• Prevention and immune tolerance for type 1 diabetes
• Prevention, genotyping and phenotypic characterization of type 2 diabetes