High-Protein Diets Reduce Liver Fat
According to a new nutritional study conducted by the German Institute of Human Nutrition (DIfE) on individuals with type 2 diabetes, high-protein diets reduced liver fat by up to 48 percent within six weeks. It did not matter whether the diet was…
How Does Friendly Fire Happen in the Pancreas?
In type 1 diabetes, the body attacks its own insulin-producing cells. Scientists at Helmholtz Zentrum München, partner in the German Center for Diabetes Research, and their colleagues at Technical University of Munich have now reported in the journal…
Videos and Presentations of Patients’ Day Available
The 4th Diabetes Patients’ Day of the Diabetes Information Service of Helmholtz Zentrum München offered information regarding the diagnosis, treatment and the latest research findings on type 1 and type 2 diabetes.
Higher risk of diabetes due to two mutations
Interaction between the obesity-risk gene FTO and the dopamine D2 receptor gene ANKK1/TaqIA on insulin sensitivity.
Diabetologia, 2016
Information about Widespread Diseases at the German Unity Day Celebration
Information about the widespread diseases diabetes, cancer and dementia generated much interest among the 450,000 guests who attended the German Unity Day celebration in Dresden (October 1st to 3rd). On the “Science Mile”, they visited the joint…
DZD Annual Report 2015 Published
The current annual report of the German Center for Diabetes Research (DZD) is available online as download.
Molecule prevents positive effect of sport
TGFβ contributes to impaired exercise response by suppression of mitochondrial key regulators in skeletal muscle.
Diabetes 2016
Smart drug clears fat from liver and blood
Scientists of DZD partner Helmholtz Zentrum München and Technische Universität München have developed a ‘smart’ drug that safely clears the liver of fat and prevents blood vessels from clogging up. Similar to a trojan horse, the drug enters the liver…
Mustard Oils from Nasturtium Influence the Cellular Glucose and Detoxification Metabolism
Nasturtium, which is also known as a medicinal plant, contains mustard oil compounds which are noticeable when eaten by their sharp taste. As a joint study by the DZD partner the German Institute of Human Nutrition (DIfE) and the Leibniz Institute of…
World Health Summit
9.-11. October 2016, Berlin
German Centers for Health Research Workshop
"Data Warehouse Systems as a Basis for Precision Medicine"
11. October 2016, 2 pm - 3:30 pm
3rd Heidelberg International Symposium on Diabetic Complications
6.-8. October 2016, Heidelberg
Mutations in FTO and Dopamine Receptor Genes Increase Risk of Obesity and Diabetes
In the development of obesity and diabetes, signals from the brain play an important role. Here an important neurotransmitter is dopamine. DZD scientists from Tübingen and Munich, together with Swedish and American colleagues, have investigated how…
Renowned Diabetes Experts and Young Researchers Exchange Ideas
At the 4th DZD Diabetes Research School in September more than 80 young scientists from all over the world informed themselves about the current status of diabetes research and presented their own results.
DZD Scientists on the Radio
On September 19th Professor Heiko Lickert, director of the Institute for Diabetes and Regeneration Research at Helmholtz Zentrum München, was on air in the radio program "IQ Science and Research" on Bavaria 2. The topic of the broadcast was…
Oktoberfest Symposium 2016 Extrinsic and intrinsic modifiers of autoimmunity and diabetes risk
27. September 2016, Munich
DDZ Symposium „Brennpunkt Diabetes: Herausforderung für Gesellschaft Versorgung und Forschung"
26. September 2016, Düsseldorf
Diabetes Is No Sweet Thing!
Telephone Campaign of "Münchner Merkur" on September 16: Diabetes Experts Answer Readers’ Questions
Genes Influence How Strongly Coffee Protects Against Diabetes
Results of various population studies suggest that people who drink lots of coffee have a reduced risk of type 2 diabetes. However, this apparently does not apply to all people in the same way. A European research team has now found evidence that…
Eating Healthy the Easy Way: Salad from the Concrete Mixer
On World Children’s Day on September 20, 2016, the initiative “SMS. Be smart. Join in. Be fit." of the German Diabetes Center, a DZD partner, will focus on healthy eating and exercise in a cooking show for children. Around 400 primary school children…
A Plant-Based Diet Can Prevent Inflammation
Being overweight or obese is often associated with chronic inflammation, which increases the risk of cardiovascular disease, type 2 diabetes and cancer. A team of scientists led by Krasimira Aleksandrova and Fabian Eichelmann of the German Institute…
4. Annual Helmholtz-Nature Medicine Diabetes Conference
18.-20. September
4. Annual Helmholtz-Nature Medicine Diabetes Conference in Munich
Islet Study Group Meeting
16.-18. September
Islet Study Group Meeting in Garmisch-Partenkirchen
DiabetesMARKT: Information about the Metabolic Disease
Diabetes now affects one in 11 adults. But how high is the personal risk of developing diabetes? What treatment options are there? Can the disease be prevented? On September 14th, a DiabetesMARKT will be held from 11:00 am to 6:00 pm at Odeonsplatz…
Metformin influences nitrogen and urea metabolism
The most frequently prescribed oral antidiabetic drug metformin significantly affects metabolic pathways. This was reported by scientists from the Helmholtz Zentrum München together with colleagues from the German Diabetes Center (DDZ) in Düsseldorf.…
52. Annual Meeting of the European Association for the Study of Diabetes (EASD)
12.-16. September 2016, Munich
International Diabetes Experts Meet in Munich
In the next few days, Munich will be the focal point of diabetes research. From September 11-20, 2016 a series of events will take place for an expected 20,000 leading researchers and diabetologists. The experts can exchange ideas at the largest…
Diabetes: Risk Factor Air Pollution
Exposure to air pollution at the place of residence increases the risk of developing insulin resistance as a pre-diabetic state of type 2 diabetes. Scientists of the German Center for Diabetes Research (DZD) reported these results in the journal…
In the Apple Orchard: A Different Way of Learning
Apfelparadies Wittlaer (Apple Paradise Wittlaer) supports the initiative “SMS. Be smart. Join in. Be fit.” of the DZD partner German Diabetes Center in Düsseldorf in its endeavor to fight childhood obesity and subsequent complications.
DZD Scientists on "Food Check with Tim Mälzer"
In the broadcast on August 29th of the TV program "Food Check with Tim Mälzer" the TV chef discussed the issue of how much sugar is good for us. The DZD scientists Prof. Matthias Tschöp, Prof. Hubert Preißl and Prof. Andreas Pfeiffer were among the…
Diabetes Highlighted in the Research Tent at the “70th Anniversary of NRW” Event
“How can I tell if I have diabetes? Does coffee protect against cardiovascular disease and diabetes? What is fatty liver?” – These were some of the questions visitors asked in the tent of the Ministry of Innovation, Science and Research (MIWF) of the…
Freder1k Study – "Early Diagnosis of the Risk for Developing Type 1 Diabetes"
The DZD scientists Prof. Dr. Ezio Bonifacio, director of the Center for Regenerative Therapies Dresden of TU Dresden, and Prof. Dr. Anette-Gabriele Ziegler, director of the Institute of Diabetes Research at Helmholtz Zentrum München, presented the…
Sugar addiction: Discovery of a brain sugar switch
Researchers at the German Center for Diabetes Research at the Helmholtz Zentrum München discovered that our brain actively takes sugar from the blood. Prior to this, researchers around the world had assumed that this was a purely passive process. An…
New Marker for Subpopulations of Beta Cells
Identification of proliferative and mature β-cells in the islet of Langerhans.
Nature 2016
Antibody dynamics reveal how fast type 1 diabetes develops in children
Antibody tests can detect the early stages of type I diabetes in affected children, even before the first symptoms of the disease occur. Researchers at the Helmholtz Zentrum München and the Paul Langerhans Institute in Dresden, both partner of the…
Breastfeeding alters maternal metabolism and protects against diabetes
An interdisciplinary team of DZD scientists at the Helmholtz Zentrum München has studied the metabolism of women with gestational diabetes after giving birth. Along with partners at other DZD institutes and the Technical University of Munich (TMU),…
The Genetic Architecture of Type 2 Diabetes
The genetic architecture of type 2 diabetes.
Nature 2016
Diabetes Researchers from Around the World Will Gather in Munich
With more than six million people affected by the disease in Germany, diabetes has become a growing health concern. From September 11–20, 2016 numerous events in Munich will be devoted to this topic. The aim is to better inform patients and lay…
Open Postdoc Positions in DZD Partner Institutes
The German Center for Diabetes Research (DZD) is inviting young scientists to apply for 10 postdoc positions in translational diabetes research at its partner institutions.
Two Honors for DZD Scientist Professor Tschöp
With more than 400 million people affected, diabetes represents a steadily increasing challenge to world health. Through his outstanding work in the field of metabolic research Matthias Tschöp of the DZD partner Helmholtz Zentrum München is…
Genetics of type 2 diabetes revealed in unprecedented detail
The largest study of its kind into type 2 diabetes has produced the most detailed picture to date of the genetics underlying the condition. Among others, the work was conducted by researchers of the Helmholtz Zentrum München and the German Center for…
Preventing type 2 diabetes: When genes fail to respond
It is widely accepted that physical exercise lowers the risk of developing diabetes. Yet in one in five participants in related studies this positive effect fails to materialize. Researchers and clinicians involved in a collaborative translational…
New Approach for Regenerative Therapy
The marker Flattop subdivides the insulin-producing beta cells of the pancreas into those that maintain glucose metabolism and into immature cells that divide more frequently and adapt to metabolic changes. This could provide a starting point for…
EURADIA Summer Meeting
Sustainable Innovation in Diabetes Research: How Europe can Rise to the Challenge
13. July 2016, Brussels
Biomarker for Figure Type: Weight Gain in the Abdomen or at the Hips?
Specific Metabolic Markers Are Associated with Future Waist-Gaining Phenotype in Women.
PLoS One 2016
DZD Scientists on WDR: Make Something of Your Genes!
The WDR television series "Quarks & Co." will feature the topic of epigenetics on July 5th. A program with the DZD scientists Prof. Johannes Beckers and Prof. Martin Hrabĕ de Angelis of Helmholtz Zentrum München will focus on the inheritance of…
Proteins can be used to predict prediabetes - Patent from the KORA study
A team of DZD researchers has developed a new method of predicting the early stages of type 2 diabetes mellitus. Their findings, published in the journal Diabetologia, show that the presence of certain proteins in blood plasma may hold the vital clue…
Donausymposium: 31st Congress of the Federation of International Danube Symposia on Diabetes mellitus (FID)
30. June - 02. July 2016, Berne
EIT Health Summer School on Big Data
27. June - 6. July
EIT Health Summer School on Big Data for Healthy Living in Geneva
New target in diabetes prevention
Alterations in β-cell calcium dynamics and efficacy outweigh islet mass adaptation in compensation of insulin resistance and prediabetes onset. dx.doi.org/10.2337/db15-1718. Diabetes 2016
Updated DIfE – GERMAN DIABETES RISK TEST Optimized for Mobile Devices
The German Institute of Human Nutrition (DIfE) has updated the online version of its German Diabetes Risk Score® and has optimized it for mobile devices. The test now takes into account the familial predisposition and is immediately accessible free…
Type 1 Diabetes: New Chance for an Old Active Agent
Scientists of the German Center for Diabetes Research have shown in an animal model that bezafibrate influences type 1 diabetes positively. The molecule improves the hepatic mitochondrial function and attenuates inflammatory processes in the liver.…
High-fat diet starves the brain
Myeloid-Cell-Derived VEGF maintains brain glucose uptake and limits cognitive impairment in obesity. doi: 10.1016/j.cell.2016.03.033. Cell 2016
Diabetes Information booth at the 14th Long Night of Science
As in recent years, the DZD partner Paul Langerhans Institute Dresden (PLID) participated actively with an information booth at the 14. Long Night of Science.
DZD Scientists as Nutrition Experts on TV
German TV broadcasters invited scientists from the German Center for Diabetes Research (DZD) to be guests on their programs to answer questions about snacks such as potato chips and also about bread as part of the daily diet.
Diabetes researchers set a good example
Sports as diabetes prevention is a longtime known fact. Scientists from DZD partner Paul Langerhans Institute Dresden (PLID) put this into practice and participated in the 8th REWE Team Challenge on June 8th, 2016. The 16 PLID Runner went along with…
Prime Minister of Saxony Stanislaw Tillich visited the Diabetes Unit at CRTD
Saxony’s Prime Minister Stanislaw Tillich visited the Center for Regenerative Therapies (CRTD) at the end of May to receive a first-hand update, amongst others, on the progress in diabetes research.
DZD-Scientists Present their Research Results at the ADA’s Diabetes Congress
DZD-Scientists Present their Research Results at the ADA’s Diabetes CongressThis year the 76th scientific sessions of the American Diabetes Association (ADA) will take place in New Orleans on June 10-14.
DIfE Symposium "Type 2 Diabetes in African Populations under Transition – The State of the Art"
07.-08. June 2016, Potsdam-Rehbrücke
One in Four 80-Year-Olds in Germany Has Type 2 Diabetes
Epidemiologists at the German Diabetes Center (DDZ), a partner of the DZD, have analyzed data of 65 million people with statutory health insurance (GKV) from the years 2009 and 2010. The result: 9.9 percent of the insured people were diagnosed with…
SMS Primary School Children Prepare Turkish Food with “KochDichTürkisch”
KochDichTürkisch invited children participating in the initiative “SMS. Be smart. Join in. Be fit." of the DZD partner German Diabetes Center to take part in a cooking class.
DFG Promotes Research into New Methods of Transplantation – DZD Partner Is Involved
The German Research Foundation (DFG) has awarded a follow-up grant worth more than EUR 15 million for a research program on xenotransplantation, which is unique in the world. The grant will fund four more years of research at TU Dresden in…
Düsseldorf SMS Primary School Children Train at Flinger Broich
Fortuna Düsseldorf offered a soccer training session to children participating in the initiative “SMS. Be smart. Join in. Be fit." of the DZD partner German Diabetes Center.
RIN Diabetes Receives the Certificate “Place of Progress”
The Regional Innovation Network (RIN) Diabetes of the DZD partner German Diabetes Center has been awarded the certificate “Place of Progress NRW 2016” by the state government of North Rhine-Westphalia. At the RIN spring meeting, Svenja Schulze,…
36. Blankenese Conference
Metabolic Control: Gut Microbiome - Cellular Circuits - Synthetic Signaling Cascades
28. May - 01. June 2016, Hamburg
Epigenetic Modification Increases Susceptibility to Obesity and Predicts Fatty Liver Later in Life
Scientists of the German Center for Diabetes Research (DZD) led by the German Institute of Human Nutrition (DIfE) have shown in a mouse model that the epigenetic* modification of the Igfbp2** gene observed in the young animal precedes a fatty liver…
Prediabetes: Fatty Liver, Visceral Obesity, impaired Production and Action of Insulin modulate Risk
Prediabetes is associated with increased risk of diabetes, cardiovascular disease, dementia and cancer. However, the disease risk considerably varies among subjects. In "The Lancet Diabetes & Endocrinology" DZD scientists have now summarized…
Epigenetic modification precedes fatty liver
Early hypermethylation of hepatic Igfbp2 results in its reduced expression preceding fatty liver in mice. doi: 10.1093/hmg/ddw121. Hum Mol Genet. April 28, 2016
Professor Roden Receives Honorary Doctorate from the University of Athens
Professor Michael Roden, director and chairman of the board of the German Diabetes Center (DDZ) and member of the board of the DZD, has been awarded an honorary doctorate from the University of Athens. In a festive ceremony, representatives of the…
SMS Primary School Children Experience Sensory Classroom
The initiative “SMS. Be smart. Join in. Be fit." of the DZD partner German Diabetes Center Düsseldorf, together with the Präha Weber School, invited the participating children to a special lesson.
New target for the treatment of fatty liver and diabetes
Fasting-induced liver GADD45β restrains hepatic fatty acid uptake and improves metabolic health. doi: 10.15252/emmm.201505801. EMBO Mol Med. May 3, 2016
Metabolism research: How fasting helps fight fatty liver disease
Scientists at Helmholtz Zentrum München have new information on what happens at the molecular level when we go hungry. Working with the Deutsches Zentrum für Diabetesforschung (German Center for Diabetes Research - DZD) and the Deutsches…
Respiratory infections as a risk factor for type 1 diabetes
Infections in Early Life and Development of Type 1 Diabetes. doi: 10.1001/jama.2016.2181. JAMA. May 3, 2016
DZD at DDG: How Bundling Research Endeavors Can Bring About Advances in Diabetes Research
Under the motto “Diabetology – Interdisciplinary”, the Diabetes Congress 2016 of the German Diabetes Society (DDG) is currently taking place (May 4-7, 2016) in Berlin. The German Center for Diabetes Research (DZD) is presenting its interdisciplinary,…
DDG Diabetes Congress
5.-7. Mai
DDG Diabetes Congress with special young scientists program
Infections can increase diabetes risk in children
Viral respiratory infections during the first six months of life are associated with an increased risk for type 1 diabetes. This is the conclusion reached by a team of scientists at the Helmholtz Zentrum München during a study published in the…
Who Takes the Most Steps? – Competition to Raise Teen Awareness about Physical Activity
A ‘step-counting competition’ has been launched using digital pedometers to raise teen awareness for getting enough regular physical activity: That is the goal of the initiative at “Z4”, a Düsseldorf youth recreation center. Studies show that the…
Optimized approach for the prevention of type 1 diabetes
Type 1 diabetes vaccine candidates promote human Foxp3(+)Treg induction in humanized mice. doi: 10.1038/ncomms10991. Nature Communications. March 15, 2016
DAAD Promotes Muscle Research Project at the DDZ
The German Academic Exchange Service (DAAD) is promoting the cooperation of researchers between the German Diabetes Center (DDZ), a DZD partner, and the University of Oslo in Norway. During the next two years, professors of the DDZ and the University…
Lifestyle is hereditary
Epigenetic germline inheritance of diet induced obesity and insulin resistance. doi: 10.1038/ng.3527. Nature Genetics. March 14, 2016
DZD Presents Current Diabetes Research and Receives the DGIM Prevention Award
The 122nd Congress of the German Society of Internal Medicine (DGIM) convened from April 9 – 12, 2016 under the theme “Demographic Change Needs Innovation”. DZD scientist Prof. Norbert Stefan was honored with the prevention award for the Tübingen…
Top Athletes Train with Düsseldorf SMS Primary School Students
Sponsors of the initiative “SMS. Be smart. Join in. Be fit." of the DZD partner German Diabetes Center give the participating children insight into their sport.
Genetic switch for the regulation of satiety and body weight
Hypothalamic Leptin Action is Mediated by Histone Deacetylase 5. doi: 10.1038/NCOMMS10782. Nature Communications. February 29, 2016
DZD Scientists on TV and Radio on World Health Day
This year’s World Health Day on April 7th focused on diabetes. Experts of the DZD were featured both at the kick-off event at the German Diabetes Center (DDZ) in Düsseldorf and also in radio and TV broadcasts.