Newsarchive 2012 to 2015 | DZD - Deutsches Zentrum für Diabetesforschung

Dr. Henrike Sell of the German Diabetes Center, a partner in the DZD, is this year’s prize recipient of the Dr. Günther and Imme Wille Foundation. The prize endowed with 10 000 euros is awarded by the Heinrich Heine University Düsseldorf to young scientists for outstanding research in the field of translational medicine and related life sciences.

[Translate to Englisch:] blau leuchtende Allianz Arena in München

On World Diabetes Day, which takes place every year on November 14th, iconic buildings throughout the world are illuminated with blue light. The German Center for Diabetes Research (DZD) is also participating in the campaign “Diabetes: protect our future” of the International Diabetes Federation (IDF). The DZD not only conducts scientific research, it also informs the general public about…

The Düsseldorf primary school children participating in the initiative "SMS. Sei schlau. Mach mit. Sei fit." (in English: Be smart. Join in. Be fit.) of the DZD scientist Professor Karsten Müssig had a lot of new activities to explore in November. First they visited the Medi-Circus created by Professor Dietrich Grönemeyer and learned what’s important for a healthy lifestyle. Then on two Fridays…

The Helmholtz Zentrum München – in conjunction with the Bavarian State Ministry of Public Health and Care Services and other cooperation partners – has today given the green light for type 1 diabetes screening across Bavaria. The Fr1da study will enable all children between two and five years of age to undergo free tests for the early detection of type 1 diabetes. The aim is to achieve early…

Physicians and scientists of the German Center for Diabetes Research (DZD) and the Competence Network Diabetes Mellitus are hosting a Germany-wide Q & A session tonight.

[Translate to Englisch:] Portrait von PD Dr. Natalia Rudovich

An international team of scientists led by Andreas F. H. Pfeiffer and Natalia Rudovich of the German Institute of Human Nutrition (DIfE), a partner in the DZD, has identified a novel adipokine secreted by fat cells into the blood, which may promote insulin resistance* and chronic inflammation in obese individuals, and thus may lead to diabetes and vascular diseases. The new findings may contribute…

Scientists at the German Diabetes Center, a partner in the DZD, have elucidated a previously unknown mechanism in the pathogenesis of the metabolic disease diabetes. The findings enable researchers for the first time to identify risk patients and to support them with a personalized therapy.

At the World Health Summit Experts Discuss How Research Results Can Reach the Patient Sooner

[Translate to Englisch:] Portrait von Prof. Matthias Tschöp

The Linda and Jack Gill Center for Biomolecular Science is honoring Prof. Dr. Matthias Tschöp from the Helmholtz Zentrum München, a partner in the DZD, with this year's Linda and Jack Gill Distinguished Scientist Award. In doing so, the Gill Center at Indiana University Bloomington is paying tribute to Tschöp's scientific achievements in the identification of the network between the brain and…

The German Center for Diabetes Research (DZD) together with the other five German Centers for Health Research (DZG) and the Federal Ministry for Research and Education (BMBF) will be part of a panel discussion at next week’s World Health Summit in Berlin: “What is translation in medicine and how to promote it? Different models in different countries”. The DZG speakers will be joined by experts…

The Annual Report 2013 of the German Center for Diabetes Research (DZD) has been published.

[Translate to Englisch:] Gruppenbild mit rund 95 Personen auf den STufen vor einem Brunnen im historischen Burghof im Stift Klosterneuburg

Around 90 young scientists, PhD students and postdocs from around the world met in mid-September in Klosterneuburg near Vienna with seven distinguished diabetes researchers for an inspiring and insightful exchange of ideas. The German Center for Diabetes Research (DZD) hosted the event.

[Translate to Englisch:] Die Preisträgerin umrahmt von den beiden DZD Vorständen.

After the Training & Education Board of the DZD had selected the award winners for 2013 last spring, the young researchers received their awards personally at the annual meeting of the EASD in Vienna. The doctoral students had held lectures or given poster presentations at national or international conferences and had submitted an abstract describing their research to the Board.

The 2nd Annual Helmholtz-Nature Medicine Diabetes Conference, held at Rilano No. 6 Lenbach Palais in Munich September 21st to 23rd, 2014, seamlessly continued the success of last year's opening conference. Top international researchers and promising young scientists took advantage of the three-day conference for an intensive exchange of ideas concerning the latest scientific findings in the field…

On September 27, 2014 the German Diabetes Centre, a partner in the DZD, the Düsseldorf diabetologists and the North Rhine-Westphalian state association of German Diabetes Aid – People with Diabetes are inviting people with diabetes, their family members as well as the general public to the 12th Düsseldorf Diabetes Day in the Düsseldorf Chamber of Trades Building. From 9:00 am to 2:30 pm visitors…

Vegetables, fruits, herbs and spices contain many phytochemicals. As a research team led by physician Andreas F. H. Pfeiffer of the German Institute of Human Nutrition (DIfE), a partner in the DZD, has shown for the first time, two of these natural substances, luteolin and apigenin, influence the intracellular pathways of insulin and reduce the in vitro glucose and lipid synthesis of human liver…

Selective insulin action in certain brain areas improves glucose metabolism throughout the body. This is a finding of a study by scientists at the German Center for Diabetes Research from the Institute of Diabetes Research and Metabolic Diseases of Helmholtz Zentrum München at the University of Tübingen, published in the journal ‘Diabetes’.

[Translate to Englisch:] EpiGlyko: neues BMBF-Forschungsprojekt zu molekularen Veränderungen bei Diabetes

What are the consequences of permanently elevated blood glucose levels on a molecular level? The BMBF-funded research project EpiGlyko - The glyco-epigenome in type 2 diabetes is seeking the answer to this question. The German-French research team is coordinated at Helmholtz Zentrum München, a partner in the German Center for Diabetes Research (DZD).

[Translate to Englisch:] Würfel mit einem Fragezeichen darauf

Germany-wide Telephone Q & A Session on November11th

[Translate to Englisch:] Portraits von Dr. Cornelia Huth (links), Prof. Dr. Karl-Heinz Ladwig

Job strain can significantly increase the risk of developing diabetes. This conclusion was based on prospective data from a population-based study conducted by scientists at the Helmholtz Zentrum München, partner in the DZD. The findings have been published in the scientific journal "Psychosomatic Medicine".

[Translate to Englisch:] Portrait von Prof. Hans.Ulrich Häring

Professor Dr. Dr. h. c. Hans-Ulrich Häring, member of the managing board of the DZD, has been elected a member of the Leopoldina, the German National Academy of Sciences. In a multi-stage selection process, the Presidium elects members who have been nominated by Academy members. Potential members must be outstanding, well-known researchers with excellent scientific achievements.

[Translate to Englisch:] Portraits von Susanne Neschen (li.) und Martin Hrabé de Angelis.

Metformin* and SGLT2 inhibitors** together reduce the blood sugar levels considerably more effectively than either drug alone. Scientists from the Helmholtz Zentrum München, partner in the German Center for Diabetes Research, report in the journal 'Diabetes’ that this is due to a synergetic mechanism.

[Translate to Englisch:] Portraits von Dr. Timo Müller (li.), Prof. Matthias Tschöp

The Best Paper Award 2014 of the Journal of Peptide Science goes to scientists of the Institute for Diabetes and Obesity (IDO) at the DZD site Helmholtz Zentrum München for the article “Restoration of leptin responsiveness in diet-induced obese mice using an optimized leptin analog in combination with exendin-4 or FGF21”.

[Translate to Englisch:] Portrait von Dr. Siegfried Ussar

The body has different types of adipose tissue that perform various metabolic tasks: white, beige and brown. For the first time, researchers at the Helmholtz Zentrum München, a partner in the DZD, and Harvard Medical School have successfully identified specific surface proteins that can help distinguish between the three types. This discovery makes it possible to develop new treatment options for…

A single molecule may provide hope for millions of people, as researchers have combined two hormones formed in the digestive tract into one novel molecule. This hormone combination acts on the receptors of insulin-stimulating hormones and is thus able to reduce blood sugar levels in patients suffering from obesity or type 2 diabetes. In the coming years, this new therapeutic approach could help…

Like every Leibniz institution, the DZD partner, the German Diabetes Center (DDZ) in Düsseldorf, is regularly evaluated by external reviewers, at the latest every seven years. Internationally recognized experts, who are informed by written documentation and an evaluation visit, assess the performance and structures of each institution. The results of the evaluation are recorded in an evaluation…

[Translate to Englisch:] Portrait von Prof. Dr. Annette Schürmann

Massive obesity increases the risk for type 2 diabetes. However, not every fat person develops the disease, because the susceptibility for type 2 diabetes in humans is to a substantial part inherited. It is not yet fully understood which gene variants play a role here. By aligning human GWAS results with two mouse models for type 2 diabetes, a team of scientists led by Annette Schürmann of the DZD…

[Translate to Englisch:] Portrait von Dr. Julia Szendrödi

For her research on obesity and diabetes mellitus, Dr. Julia Szendrödi, Ph.D., director of the Clinical Research Center (CRC) unit at the German Diabetes Center (DDZ) in Düsseldorf, which is a partner in the DZD, has received the Young Investigator Award of the European Association for the Study of Obesity, (EASO). The award was presented to her at this year’s EASO Annual Meeting in Sofia,…

Scientists at the DZD partners in Munich and Dresden aim to investigate T-cell mediated immunoreactions involved in type 1 diabetes to find out what processes influence the progress of the disease. The Juvenile Diabetes Research Foundation (JDRF) supports the research project with a grant of 550.000 US-Dollars.

[Translate to Englisch:] Portraits von Prof. Dr. Philippe Schmitt-Kopplin, Alesia Walker

An increase in body weight is accompanied by changes in both the composition of gut microbiota and the pattern of thousands of metabolites. In addition, diabetes appears to influence certain metabolic pathways, such as sulfur metabolism. Scientists from the Helmholtz Zentrum München, a partner in the DZD, used metabolomic analyses to examine these effects and consequently have again pointed out…

[Translate to Englisch:] Ski-Star Rosi Mittermaier mit Nordic Walking Stöcken vor dem Stand des DZD

During the campaign day "Diabetes bewegt uns!" / “Diabetes Challenges Us!” of the Bavarian Ministry of Health on July 12th at Odeonsplatz in Munich, the German Center for Diabetes Research (DZD) was the point of contact for the interested public and those affected by the disease. At a joint information stand with the Diabetes Information Service Munich and the Institute of Diabetes Research of…

Professor Ziegler sums up the research successes of recent years, particularly with regard to early diagnosis of type 1 diabetes. The renowned diabetes researcher and director of the Institute of Diabetes Research at Helmholtz Zentrum München, a partner in the DZD, is optimistic about the future, which offers a perspective of even better and more personalized treatment options and the legitimate…

As part of the project “Diabetes at School” of the DZD partner German Diabetes Center in Düsseldorf, Daniel Schnelting, multiple-time German champion in sprint, is training with children of a Düsseldorf elementary school.

The German Center for Diabetes Research (DZD) Presents Itself to the Medical Public

At the Diabetes Conference of the German Diabetes Association (DDG), which took place in Berlin at the end of May, two DZD scientists were awarded prizes. PD Dr. Natalia Rudovich received the Menarini Prize and Dr. Barbara Ludwig received the Ernst Ludwig Pfeiffer Award.

On June 11th Prof. Tilman Grune will be installed as scientific director of the German Institute of Human Nutrition Potsdam-Rehbrücke (DifE) by the Brandenburg Minister for Science, Research and Culture, Prof. Sabine Kunst. He thus succeeds Prof. Hans-Georg Joost, who was scientific director of the DZD partner institute for more than 12 years. Grune’s position will be connected with the Chair of…

[Translate to Englisch:] Kinder im Fussballdress mit Bällen trainierend.

The children participating in the initiative "SMS. Sei schlau. Mach mit. Sei fit." (in English: Be smart. Join in. Be fit.) of the DZD partner German Diabetes Center in Düsseldorf are completing a training session offered by the Fortuna soccer team at the Flinger Broich soccer stadium and sports center.

[Translate to Englisch:] Gruppenbild der Workshop-Teilnehmer

The German Diabetes Center, a partner in the DZD, invited participants for the sixth time to the Protein Rainbow Workshop in Düsseldorf. This year the participants informed themselves about the latest methods to analyze and separate proteins and tested these methods on their own samples.

DZD scientists at the German Institute of Human Nutrition (DIfE) have optimized the Diabetes Risk Test* on the basis of new study data. Together with other colleagues, they published the optimized test in the journal Diabetes Research and Clinical Practice (Mühlenbruch et al., 2014). The new questionnaire versions, which now also factor in a family history of diabetes, are available free of charge…

The successful development of a new diabetes drug – an SGLT2 inhibitor – from the test tube to the patient was presented in a fascinating lecture by Professor William Washburn at Helmholtz Zentrum München. The lecture was organized by the German Center for Diabetes Research (DZD), the Helmholtz Diabetes Center (HDC) and the pharmaceutical company AstraZeneca.

We are pleased to announce the 2nd Annual Helmholtz-Nature Medicine Diabetes Conference. This meeting will be held on September 21-23, 2014, at the Rilano No. 6 Lenbach Palais in Munich, Germany.

As part of the initiative “SMS. Be smart. Join in. Be fit.”, the German Diabetes Center in (DDZ) Düsseldorf, a partner in the DZD, organized a fitness breakfast on May 5th for primary school children. This event with the theme of health and exercise also raised awareness for diabetes prevention.

A collaborative study by an international team of scientists published in the prestigious journal Proceedings of the National Academy of Sciences (PNAS) shows that the Notch signaling pathway is essential for the formation of insulin-producing beta cells. The results of the study indicate new starting points for the treatment of diabetes mellitus based on beta cell replacement therapy and the…

[Translate to Englisch:] schlafendes Baby

Data from the Potsdam EPIC* Study have now shown that women who have breastfed have about a 40 percent reduced risk of developing type 2 diabetes compared to women who did not breastfeed. Biomarker analyses conducted in the study indicate that prolonged breastfeeding is associated with a long-term improved metabolic profile of the mother. The data have now been published in the current issue of…

Prof. William Washburn will present his data on "Dapagliflozin - from Bench to Bedside" on Friday May 16th, at the Helmholtz Zentrum München. Scientists and doctors are invited to join

For his outstanding work in the field of clinical and experimental research to achieve a better understanding of hypoglycemia in people with diabetes, Prof. Dr. Michael Roden, board member of the German Center for Diabetes Research (DZD), has been honored with the Somogyi Award 2014.

Neuherberg, Germany 28 April 2014. The Paul Martini Foundation is honouring Prof. Dr. Matthias Tschöp, diabetes researcher at the Helmholtz Zentrum München, with this year's Paul Martini Prize. In doing so the foundation, which funds important drug research, is paying tribute to Tschöp's scientific achievements in the identification and development of new therapy concepts for diabetes and obesity.

[Translate to Englisch:] Portraits von Dr. Christiane Winkler, Jennifer Raab

Low levels of vitamin D are commonly found in people with type 1 diabetes. But even children who have multiple positive islet autoantibodies without manifest type 1 diabetes have lower levels of vitamin D in their blood. This does not appear, however, to influence the progression of the disease from pre-diabetes to diabetes, according to scientists from the Helmholtz Zentrum München, a partner in…

People who have parents with type 2 diabetes may have up to a 2.9-fold increased risk for this disease. This is suggested by results of the Potsdam EPIC* study – a large-scale, population-based longitudinal study with more than 27,000 study participants. The findings of the research team led by DZD scientists Matthias Schulze and Kristin Mühlenbruch of the German Institute of Human Nutrition…

Scientists led by Dr. Hubert Preißl and Prof. Andreas Fritsche of the University Hospital Tübingen and the German Center for Diabetes Research (DZD) have currently published a study in "Diabetologia" (Journal of the European Association for the Study of Diabetes), which provides evidence for the first time of an association between maternal insulin action (= insulin sensitivity) and the brain…

People with type 2 diabetes who report good self-management behavior have a reduced mortality risk. This was the result of a population-based study conducted by scientists at Helmholtz Zentrum München in the context of DZD research fields emphasizing the great importance of patient behavior in the diabetes treatment process. These findings were published in the journal ‘Diabetes Care’

On April 9, 2014 the German Diabetes Center (DDZ), a partner in the DZD, is organizing an information day for the third time. Current developments in the field of diabetes research and the findings of the German Diabetes Study will be presented. The participants will have the opportunity to undergo diabetes-related examinations.

[Translate to Englisch:] Prof. Roden am Rednerpult vor DZD-Plakat

Scientists of the German Center for Diabetes Research (DZD) provided insights into the latest findings and trends of diabetes research at the 57th Symposium of the German Society of Endocrinology (DGE). Genetic aspects in the development of type 2 diabetes and possible future therapy concepts were the focus of a separate DZD lecture session on the opening day. The meeting of the experts in…

The interactions of the gut microbiota in children with typical diabetes autoantibodies differ from that in healthy children. The fact that these differences already exist before antibodies are detectable in the blood adds to the growing evidence that microbial DNA, the so-called microbiome, may be involved in the development of autoimmune processes. Scientists from the Helmholtz Zentrum München…

Patients with LADA – a form of autoimmune type 1 diabetes in adulthood – can be distinguished from patients with non-autoimmune type 2 diabetes by means of the antibody reaction affinity to the enzyme glutamic acid decarboxylase (GAD). Scientists from the Helmholtz Zentrum München have reported in the journal 'Diabetes Care' that high-affinity GAD antibodies are found in patients who produce only…

[Translate to Englisch:] Portrait von Prof. Anette-Gabriele Ziegler

Diagnosis of type 1 diabetes is preceded by the appearance of pancreatic islet cell autoantibodies circulating in the blood. Scientists of Helmholtz Zentrum München and the University of Dresden, both partners in the DZD, in cooperation with colleagues from the University of Cambridge, have now found a transient, significant increase in the expression of antiviral interferon (IFN) immune response…

The German Center for Diabetes Research (DZD) presented itself to Japanese diabetes scientists as point of contact for an international exchange about the status of research and prevention of the widespread disease diabetes. On February 13, 2014 representatives of German diabetes organizations met at Helmholtz Zentrum München with scientists of the National Center for Global Health and Medicine in…

In the current issue of Lancet Diabetes & Endocrinology, scientists of the German Center for Diabetes Research (DZD) and the University Hospital of Vienna led by Professor Dr. Norbert Stefan have published their results of a joint clinical trial on the treatment of non-alcoholic fatty liver disease**. By inhibiting the enzyme 11-β-hydroxysteroid-dehydrogenase 1 (11-βHSD1), the research group was…

[Translate to Englisch:] Auslage mit verschiedenen Gemüsen

The European Research Commission will fund the interdisciplinary project “Nudge-it” with nine million euros. DZD scientists from Tübingen are among the research groups from six European countries who will study the metabolic, neurobiological, psychological and social foundations of our eating behavior.

Dr. Claudia Wiza, a young researcher at the German Diabetes Center, a partner in the DZD, has been awarded the Dr. Eickelberg Foundation Prize 2013. Dr. Wiza received the award for her outstanding work on the development of insulin resistance.

In its TV series “Gesundheit (Health)” on January 28, 2014, Bavarian Radio included a feature about non-alcoholic fatty liver disease (NAFLD). In the broadcast entitled “An Underestimated but Widespread Disease”, DZD scientist Professor Norbert Stefan of the University Hospital Tübingen talked about NAFLD. Referring to the example of a patient, Stefan showed how a change in lifestyle – here a…

A grant of 6 million euros for the HumEn project brings together leading European stem cell-research groups and industrial partners in a coordinated and collaborative effort aimed at developing glucose-responsive, insulin-producing beta cells for future cell-replacement therapy in diabetes. The project will contribute significantly to better treatment and quality of life for the increasing…

DZD scientists Decipher Early Molecular Mechanisms of Differentiation: The Wnt/β-catenin signaling pathway and microRNA 335 are instrumental in helping form differentiated progenitor cells from stem cells. These are organized in germ layers and are thus the origin of different tissue types, including the pancreas and its insulin-producing beta cells. With these findings, Helmholtz Zentrum München…

Die Klinische Kooperationsgruppe „Subklassifikation von Typ 2 Diabetes“ erhielt Ende letzten Jahres für die Studie PPS-Diab (Prediction, Prevention and Subclassification of Type 2 Diabetes) den Heinrich-Sauer-Preis 2013 des Diabeteszentrums Nordrhein-Westfalen. Die KKG wird vom Klinikum der Ludwig-Maximilians-Universität München und dem Helmholtz Zentrum München, einem Partner im DZD, gemeinsam…

Warum erkranken manche Menschen an Krebs, andere nicht? Wer ist anfällig für Altersdiabetes? Viele Krankheiten sind eng mit unserer DNA gekoppelt; bestimmte DNA-Marker signalisieren ein erhöhtes Krankheitsrisiko, zum Beispiel für Brustkrebs. Allerdings ist meist unklar, welche DNA-Varianten tatsächlich eine Krankheit auslösen – und auf welchem Weg. Mit einem neuen Verfahren haben u.a.…

[Translate to Englisch:] Portraits Dr. Clemmensen und Dr. Müller

A single molecule, which acts equally on the receptors of the metabolic hormones glucagon and glucagon-like peptide-1 (GLP-1) improves body weight and diabetes through restored function of the anti-obesity hormone leptin. This was discovered by an international team comprising scientists from the Helmholtz Center Munich, a partner in the DZD, Indiana University and the San Diego-based biotech…

The German Center for Diabetes Research wishes you merry christmas and a happy new year.

Upon the initiative of academy member Professor Ivan I. Dedov, president of the Russian Academy of Medical Science (RAMS), and Professor Helmut Hahn, foreign member of RAMS and chairman of the Koch- Metschnikow Forum (KMF), the “First Russian-German Conference in Endocrinology/Diabetology” took place in Moscow on October 24-25, 2013 with the participation of the DZD.

“Type-1-diabetes: is it possible to delay the disease?” was the title of the report on Bavarian television’s science show „Gesundheit“ („Health“) on November 26. The telecast (in German only) dealt with Prof. Dr. Anette-Gabriele Ziegler’s diabetes research at the Helmholtz Zentrum München.

The Annual Report 2012 of the German Center for Diabetes Research (DZD) has been published.

Professor Sabine von Schorlemer, Minister of the Saxon Ministry of Science and Art, visited the diabetes research center, the Paul Langerhans Institute Dresden (PLID) at the Carl Gustav Carus University Hospital, on November 13, 2013 – the day before World Diabetes Day – to learn about the current status of diabetes research. Since June 2013, the PLID, a partner of the German Center for Diabetes…

[Translate to Englisch:] Nachtaufnahme der blauen Allianz Arena hinter Parkgarage und Autobahn mit roten Lichtstreifen.

On World Diabetes Day, November 14th, distinctive buildings shall be lit up in blue in various locations in Germany. The German Center for Diabetes Research (DZD) is involved in this year’s campaign “Protect Our Future” of the International Diabetes Federation (IDF). The aim is to raise global awareness of diabetes, which affects around six million people in Germany alone.

Each year 36 million people across the globe die of noninfectious diseases such as diabetes, cardiovascular diseases and cancer. Common risk factors for these diseases are physical inactivity and eating too much of the wrong foods, which lead to excess weight and insulin resistance. American, Finnish and German studies have now shown that lifestyle changes with more physical exercise and a…

[Translate to Englisch:] Portrait von Prof. Dr. Matthias Tschöp

In the current issue of the scientific journal ‘Nature’ researchers suggest that the brain has an important impact on maintaining blood glucose metabolism.

[Translate to Englisch:] Prof. Ron Kahn mit Mikrofon in den Zuhörerreihen in der Casa Convalescencia der Uni Barcelona

Five internationally renowned scientists gave graduate students and postdocs from around the world insight into the latest results and trends in diabetes research. The young researchers met at the invitation of the German Center for Diabetes Research (DZD) on November 6, 2013 for the first DZD International Diabetes Research School. The event took place prior to the high-profile XII International…

The sensitivity of the GLP-1 hormone, which is secreted by the gastrointestinal tract, can predict the metabolic efficacy of a gastric bypass. The use of a GLP1 challenge could thus function as a novel predictive biomarker for personalized treatment of type 2 diabetes and obesity. These findings were reported by scientists of Helmholtz Zentrum München and the University of Cincinnati, Ohio, USA in…

[Translate to Englisch:] Dr. Heike Vogel im Labor beim Pipettieren

On November 12, 2013, the State of Brandenburg will present the Brandenburg Young Scientist Award to the best young researchers of the year. The award ceremony, which is being held this year for the seventh time, will take place in the House of Brandenburg-Prussian History in Potsdam. Among the award winners is the DZD biologist Dr. Heike Vogel from the German Institute of Human Nutrition…

[Translate to Englisch:] Portrait von Janine Kröger

A diet that is low in sugar-sweetened beverages, processed meat and white bread is associated with a reduced risk of type 2 diabetes. This is the result of a large longitudinal observational study that examined the eating habits of people from seven European countries. The study comprised data of 21,616 women and men, 9,682 of whom developed type 2 diabetes during the observation period. The…

[Translate to Englisch:] Portrait von Dr. Brian Finan

Scientists from the Helmholtz Zentrum München (HMGU), a partner in the DZD, and the Technische Universität München (TUM), together with scientists in the USA, have developed a new therapeutic approach for treatment of type 2 diabetes. A novel single molecule hormone, which acts equally on the receptors of the insulin-stimulating hormones GLP-1 and GIP, was observed to reduce weight and improve…

[Translate to Englisch:] Portraits von Dr. Susanne Hofmann (IDR, li.) und Dr. Maarit Lehti

High density lipoprotein cholesterol (HDL), the so-called “good“ cholesterol improves blood glucose levels by enhancing skeletal muscle function and reducing adiposity, scientists of the Helmholtz Zentrum München report in the current issue of the renown American Heart Association Journal ‚Circulation‘.

In two comprehensive studies, scientists from the Helmholtz Zentrum München (HMGU), a partner in the DZD, Ludwig-Maximilians-Universität München (LMU) and Technische Universität München (TUM) have discovered new associations of two major type 2 diabetes risk genotypes and altered plasma concentrations of metabolic products. The "Virtual Institute Diabetes" (VID) joint research cooperation is…

[Translate to Englisch:] Portrait von Prof. Bornstein vor Bücherregal

Diabetes researchers at Carl Gustav Carus University Hospital Dresden, a partner of the German Center for Diabetes Research, have implanted the world’s first successful artificial pancreas system into the body of a type 1 diabetes patient. The human islet cells of this bioreactor system reliably produced insulin for nearly a year.

The results of a large-scale longitudinal observational study suggest that people with diabetes do not require different dietary and lifestyle recommendations than the general public. According to these new study data, they benefit even more from the usual recommendations than nondiabetic individuals. Diewertje Sluik, who conducted the research in the Department of Epidemiology of the German…

The joint diabetes conference of Helmholtz Zentrum München,a partner in the DZD, and Nature Medicine, which took place September 22-24, was a great success. Designed to find potential solutions to the preeminent scientific challenges facing type 2 diabetes and obesity, the conference fully delivered on its objectives. It provided a unique platform for knowledge exchange in the field of diabetes…

Scientists from the Helmholtz Zentrum München, a partner in the DZD, in cooperation with the University of Cincinnati, USA, have discovered that the placement of a non-permeable tube in the small intestine leads to reduced nutrient absorption and consequently to reduced obesity and enhanced glucose metabolism. These findings are published in the current issue of the British medical journal 'Gut'.

[Translate to Englisch:] V.l.: Monika Grüßer, Vice-Direktorin EASD, Brigitte Fröhlich, DZD, Andrew Boulton EASD-Präsident, João Nabais, Präsident IDF Europe vor dem DZD-Stand im Associations' Village des EASD

The German Center for Diabetes Research (DZD) presented itself extensively at the 49th Annual Meeting of the European Association for the Study of Diabetes (EASD) from September 23 – 27, 2013 in Barcelona.

[Translate to Englisch:] Portraits von Dr. Stefanie Hauck (links), Dr. Alice Ly

Damage to the retina due to diabetes can be ameliorated only partially, despite treatment with the standard drug metformin. Scientists of Helmholtz Zentrum München have discovered that metformin treatment normalizes the alterations induced by diabetes in only about half of the altered retinal proteins. The results of the study were published in the journal Diabetologia.

[Translate to Englisch:] 1. Bild: Drei Personen vor Roll-up des DZD

Around 150 experts from academia and industry convened on September 18th, 2013 in Lund, Sweden at the IDEA Summit (Innovation in Diabetes: European Action Summit 2013) to discuss strategies for the development of innovative diabetes therapies. To counteract the emerging worldwide epidemic of type 2 diabetes, research gaps and bottlenecks must be identified and overcome. The conclusion of the…

[Translate to Englisch:] Studienteilnehmerinnen auf Liegen, denen von Krankenschwestern Blut abgenommen wird.

Metabolic syndrome is characterized by obesity, high blood pressure, disturbed lipid metabolism and insulin resistance of body cells. People who suffer from this lethal quartet are at greater risk for developing diabetes, cardiovascular diseases and specific cancer diseases. As scientists in the research group of Natalia Rudovich and Andreas F. H. Pfeiffer of the German Institute for Human…

[Translate to Englisch:] Eltern mit drei kleinen Kindern auf einem Spaziergang.

Through the detection of islet autoantibodies, type 1 diabetes can often be diagnosed years before the onset of the autoimmune disease. In many cases, the disease progresses so slowly that enough time remains for a preventive immunotherapy, as is offered in the new Oral Insulin Study of the Institute of Diabetes Research in Munich. In the previous DPT trial (Diabetes Prevention Trial – Type 1),…

Professor Dr. Matthias Tschöp has been elected a member of the Leopoldina, the German National Academy of Sciences. In a multi-stage selection process, the Presidium elects members who have been nominated by Academy members. Potential members must be outstanding, well-known researchers with excellent scientific achievements.

[Translate to Englisch:] Portraits von Dr. Katharina Warncke; Dr. Andreas Beyerlein

Funded by the DZD, the DiMelli study examines the different phenotypes of diabetes mellitus in relation to their immunological, metabolic and genetic profiles. Although the formation of autoantibodies is associated with specific clinical features such as metabolic markers, the various forms of diabetes cannot be clearly delineated on the basis of this association, and in many cases there is…

Metabolically healthy obesity – where an individual has a Body Mass Index (BMI) greater than 30, but does not appear to be at increased risk of the health complications usually associated with excess weight – has only been recently widely recognised by medical practitioners. But as global levels of obesity continue to rise, identifying metabolically healthy obese patients could be of critical…

[Translate to Englisch:] Gruppenbild der Teilnehmer und Dozenten des Rainbow Workshops am Deutschen Diabetes-Zentrum in Düsseldorf

Current methods of bioanalysis were the focus of the fifth Protein Rainbow Workshop at the German Diabetes Center in Düsseldorf. At the international event, young scientists learned about the latest methods to detect proteins and were able to analyze their own samples using these techniques. The workshop is part of the Training & Education Program for young scientists of the German Center for…

[Translate to Englisch:] Portrait von Prof. Dr. Anette-Gabriele Ziegler

In recognition of her significant clinical research in the field of type 1 diabetes, Prof. Dr. Anette-Gabriele Ziegler of Helmholtz Zentrum München, a partner in the DZD, has received the Mary Tyler Moore and S. Robert Levine Excellence in Clinical Research Award of the Juvenile Diabetes Research Foundation (JDRF), a foundation which promotes type 1 diabetes research.

A study involving more than 8,000 participants has shown that people with a family history of diabetes see their risk of prediabetes increase by 26%. The research is published in "Diabetologia", the journal of the European Association for the Study of Diabetes, and is by Dr Andreas Fritsche and colleagues from the German Center for Diabetes Research.

Renowned scientists from all over the world meet again in Munich to present and discuss new results from their research on our 7th traditional "Wiesn Symposium". This year's event topic is "Shaping Type 1 Diabetes". It is focused on shapes - the shapes of type 1 diabetes and the factors that shape or could change the development of type 1 diabetes.

The Oktoberfest Symposium 2013 is organized by…

[Translate to Englisch:] Portraits of Dr. Martin Jastroch; Dr. Carola Meyer

Scientists at Helmholtz Zentrum München and the University of Marburg have found that thermogenesis in mammalian brown adipose tissue is a mechanism that has long existed in the course of evolution. The findings provide a new basis to characterize energy metabolism and the components involved, as the scientists report in the journal "Nature Communications".

[Translate to Englisch:] Farbaufnahme von Langerhans'schen Inseln

We are pleased to announce the 1st Annual Helmholtz-Nature Medicine Diabetes Conference. This meeting will be held on September 22-24, 2013, at the Residenz, the former royal palace of the Bavarian monarchs, in Munich, Germany. The German Center for Diabetes Research (DZD) is a partner in this new event.

[Translate to Englisch:] Portrait von Prof. Dr. Eckhard Lammert

On July 16, 2013 the German Diabetes Center (DDZ), a partner in the DZD, will open a new institute – the Institute for Beta Cell Biology. In this organizational unit under the direction of Prof. Dr. Eckhard Lammert, research on beta cells at the DDZ will be accorded the status of an institute.

DZD Scientist Receives Research Prize of the Dr. Günther and Imme Wille Foundation

Blue Landmark Buildings and Expert Tips for World Diabetes Day

Kids of the SMS Initiative Visit the Medi-Circus and Try Out Taekwando

Type 1 diabetes: Early detection – Good treatment in early stages

Today: Diabetes experts are answering your questions!

Researchers Identify Novel Adipokine Linked to Chronic Inflammation

DZD Researchers Decipher Mechanism of Diabetes Development

Ensuring That Patients Benefit from Research

DZD researcher receives 2014 Gill Distinguished Scientist Award

World Health Summit: DZGs holding Panel Discussion about Translational Medicine

DZD Annual Report 2013

2nd DZD Diabetes Research School: Ambition Meets Experience

DZD Awards Presented to Young Diabetes Researchers

2nd Helmholtz-Nature Medicine Diabetes Conference a great success

12th Düsseldorf Diabetes Day – Living Well with Diabetes and Avoiding Complications

Plant Compounds Have A Beneficial Effect on the Glucose Metabolism of Liver Cells

Demonstrated for the first time directly in humans: Insulin action in the brain regulates glucose metabolism

EpiGlyko: New BMBF Research Project on Molecular Alterations in Diabetes

Optimal Management of Diabetes – Experts Answer Questions about Diabetes

Work-related stress is a risk factor for type 2 diabetes

Professor Hans-Ulrich Häring Elected Member of the Leopoldina

Diabetes: A duo helps better

Best Paper Award 2014 for DZD Scientists

Hope for the overweight

Fighting fat with a single molecule

German Diabetes Center Evaluated Positively

20 Genes Confirmed as Diabetes Genes: DZD Sheds Light on Diabetes Pathogenesis

DZD Scientist Receives Young Investigator Award

JDRF research grant for type 1 diabetes research

Weight gain influences intestinal bacteria and metabolite patterns

DZD Active Participant in “Diabetes Challenges Us!”

A Public Call for More Research on Diabetes – An Interview with Prof Dr. Anette-G. Ziegler

Fit with Diabetes: Training with Sprinter Daniel Schnelting

Practice-Oriented Diabetes Research – News from the Diabetes Congress

Honors for DZD Scientists

Tilman Grune New Scientific Director of the DZD Partner DIfE

SMS Diabetes Initiative: Düsseldorf Elementary School Students in Soccer Fever

Analyzing Proteins in Two Dimensions – Rainbow Workshop at the DDZ

German Diabetes Risk Test Optimized by DZD Scientists

Lecture on the Successful Development of a Diabetes Drug

2nd Annual Helmholtz-Nature Medicine Diabetes Conference

With a Balanced Breakfast Fit for the School Day

Important Signals Identified for the Targeted Development and Regeneration of Beta Cells

Mothers Who Breastfeed Have a Reduced Risk of Type 2 Diabetes

From Bench to Bedside: Scientific discussion with the founder of Dapagliflozin

DZD Board Member Michael Roden Honored with Somogyi Award 2014

Diabetes researcher Matthias Tschöp receives 2014 Paul Martini Prize

Type 1 diabetes: Vitamin D deficiency occurs in an early stage

Near Three-fold Risk of Diabetes in Children of Parents with Type 2 Diabetes

Are Obesity and Diabetes Pre-programmed in the Womb?

Diabetes: Good Self-Management Helps to Reduce Mortality

Diabetes Information Day in Düsseldorf

DZD presents "News about Type 2 Diabetes" at the DGE Symposium

Type 1 diabetes: Gut microbiota networks may influence autoimmune processes

Type 1 diabetes in adults: Antibody affinity is decisive

Molecular Evidence of Imminent Disease Development for Type 1 Diabetes

DZD Exchange with Japanese Delegation about Diabetes Research and Prevention

First Joint Clinical Trial of the DZD Is Published

DZD Scientists Participate in an Interdisciplinary EU Project on Nutrition

Dr. Eickelberg Foundation Prize Goes to DZD Scientist

Link between non-alcoholic fatty liver disease and diabetes: a TV report

Stem cell research: New, major EU research grant focused on stem cell-based treatment of diabetes

Insulin-Producing Beta Cells from Stem Cells

Research award for KKG Type 2 Diabetes

Higher diabetes risk due to disturbed gene experssion

Multihormone reverses metabolic damage of high calorie diet

Merry christmas and a happy new year!

First Russian - German Conference on Endocrinology/Diabetology

“Type-1-diabetes: is it possible to delay the disease?” – a television report

DZD Annual Report 2012

Paul Langerhans Institute Receives Direct Funding from the Free State of Saxony

Glowing Blue: World Diabetes Day – DZD Takes Part in the Blue Monument Challenge

Lifestyle Change Not Enough for High-Risk Individuals

The role of the brain in blood sugar metabolism

Inspiring First DZD Diabetes Research School for Young Researchers

Gut Hormone Test Predicts Individual Efficacy of Gastric Bypass

Dr. Heike Vogel Receives Brandenburg Young Scientist Award

Lower Intake of Soft Drinks, Processed Meat and White Bread Linked to Lower Diabetes Risk

New multiple action intestinal hormone corrects diabetes

HDL cholesterol controls blood glucose