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A study by the University Hospital of Tübingen, Helmholtz Munich and the German Center for Diabetes Research (DZD) has provided new insights into the role of the brain as a crucial control center and the origin of obesity and type 2 diabetes. The hormone insulin plays a key role in the development of obesity.

Overweight man and female doctor look at the data on a tablet that the doctor is holding in her hand. — © 2023 Halfpoint/Shutterstock.

The brain's sensitivity to insulin is associated with long-term weight gain and unhealthy body fat distribution. What specific functions does insulin perform in the brain, and how does it affect individuals of normal weight?

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Obesity Starts in the Brain