IFIS
The IFIS (Intermittent Fasting to Improve Insulin Secretion) study aims to investigate the effect of intermittent fasting on insulin secretion in people with prediabetes and diabetes and an increased risk of secondary diseases.
The study is being carried out at several locations across Germany.
The prediabetes part is completed. Only patients with diabetes will be included in the study.
Background of the Study:
Previous clinical studies have shown the beneficial effects of intermittent fasting on weight loss and metabolism. Now the effect of intermittent fasting on blood glucose metabolism and body fat content is to be examined in detail.
Suitable Participants:
- Men and women between the ages of 18 and 70 years
- Elevated blood glucose levels, but not yet diabetes (prediabetes), or
- Newly manifested type 2 diabetes (diagnosis <5 years)
- No therapy with insulin or glitazones (with other diabetes therapy a "washout period" is necessary)
Course of the Study:
The duration of the study is approximately 6 weeks, during which the participants are either instructed to follow a standard diet or to lose weight according to the principle of intermittent fasting. A follow-up examination is planned after 6 months.
The participants will receive detailed metabolic examinations as well as scientifically based dietary counseling from specialist staff.
Participating Clinics:
Participating Clinics:
Tübingen
Prof. Dr. Andreas Fritsche, Prof. Dr. Reiner Jumpertz-von Schwartzenberg
Tübingen University Hospital
Phone: +49 (0)7071–2980687
stoffwechsel@med.uni-tuebingen.de
Düsseldorf
Prof. Dr. Michael Roden, Prof. Dr. Robert Wagner
German Diabetes Center
Phone: +49 (0)211- 3382209
studienzentrum@ddz.de
Berlin/Potsdam
Dr. Stefan Kabisch
German Institut for Human Nutrition /
Charité Berlin
Phone: +49 (0)30-450 514 439
diabetes@charite.de
Dr. Olga Ramich
Phone: +49 (0)33200 88 2760
German Institut for Human Nutrition
dzd@dife.de
Dresden
Prof. Dr. Nikolaos Perakakis, Doreen Ziehl
Dresden University Hospital
Phone: +49 (0)351-458 11722
Doreen.Ziehl@uniklinikum-dresden.de
Leipzig
Dr. Gesine Flehmig
Leipzig University Hospital
Phone: +49 (0)341-97 20 728
dzd@medizin.uni-leipzig.de
https://www.uniklinikum-leipzig.de/einrichtungen/medizinische-klinik-3/en/division-of-endokrinology
Lübeck
Prof. Dr. Stefan Kopf
Dr. Svenja Meyhöfer
Universitätsklinikum Schleswig-Holstein
Julia Altrogge
Tel.: 0451 31017863
Lara Braun
Tel.: 0451 31017864
dds@uksh.de
München - TUM
Dr. Bärbel Huber
Technical University Munich
Tel: 089 289 24915
baerbel.huber@tum.de
München - LMU
Prof. Dr. Jochen Seißler
Ludwig-Maximilians-Universität
Tel.: 089–4400–52234
studienzentrum-diabetes@med.uni-muenchen.de
Heidelberg
Dr. Alba Sulaj
Dr. Zoltan Kender
Heidelberg University
Phone: +49 (0)6221- 56-8606
stoffwechsel.studien@med.uni-heidelberg.de