Main research topics – DZD Academies
The DZD is working on the most pressing issues in diabetes research. # What influence do liver or brain have on diabetes? # How do environmental factors such as diet affect the activity level of genes? # How can beta cells be protected? # What other diseases are associated with diabetes? # How can metabolic disease be prevented? # How does the autoimmune disease type 1 diabetes develop?
In order to be able to investigate these questions, the DZD is focusing on the following research topics (DZD Academies):
Type 1 diabetes – prevention of the autoimmune disease
Development of a therapy that regulates the immune system in a way that prevents the destruction of beta cells.
Prevention of type 2 diabetes
The aim is successful personalized diabetes prevention.
Complications of diabetes
Diabetes can lead to various serious complications. To avoid or delay such consequences in the future, it is important to identify which patients have a high risk of complications.
The influence of genetics and epigenetics on the development of diabetes
Research into the genetic and epigenetic mechanisms in metabolism in animal models and in human samples.
Causes and treatment of non-alcoholic fatty liver disease
Obesity and type 2 diabetes are closely related to non-alcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH).
Metabolic Control by the Brain
Studies have shown that insulin resistance of certain brain areas has a negative effect on metabolism.
Protection and regeneration of beta cells
The elucidation of the mechanisms of destruction and/or functional impairment of beta cells as a prerequisite for new therapeutic approaches.