Diabetes Drug from the Group of SGLT2 Inhibitors Normalizes Insulin Action in the Brain

Tübingen

Overweight or obesity, an unfavorable distribution of fat in the body and the development of type 2 diabetes are often associated with a reduced effect of the hormone insulin in many organs, including the brain (insulin resistance). So far…

People with High-Risk Prediabetes Benefit from Intensive Lifestyle Intervention

Tübingen

Intensive lifestyle intervention with plenty of exercise helps people with prediabetes improve their blood glucose levels over a period of years and thus delay or even prevent type 2 diabetes. In particular, individuals with prediabetes at…

How Regular Exercise Can Protect Against Fatty Liver Associated Diseases

Tübingen

Exercise not only trains the muscles but can also prevent the development of fatty liver. A new study by the German Center for Diabetes Research (DZD), Helmholtz Munich and Tübingen University Hospital shows which molecular adaptations, in…

Young Talents and Renowned Diabetes Researchers in Exchange

Neuherberg

At the DZD Diabetes Research School of the German Center for Diabetes Research (DZD) international diabetes experts informed more than 250 young scientists about the latest developments in diabetes research. The online event took place in…

World Diabetes Day 2021: German Diabetes Center Calls on Policymakers to Take Action

Düsseldorf

This year marked the 30th anniversary of World Diabetes Day. In the course of this event, not only was a health market opened in Düsseldorf with illumination of important monuments, but the German Diabetes Center also held a press…

New Link between Diet, Intestinal Stem Cells and Disease Discovered

Neuherberg

Obesity, diabetes and gastrointestinal cancer are frequently linked to an unhealthy diet. However, the molecular mechanisms responsible for this are not fully understood. Researchers at Helmholtz Munich have gained some new insights that…

MTZ Award 2021

Dr. Corinna Niersmann Receives MTZ® Award 2021

Düsseldorf

For her research on the influence of the adipokine omentin on the development of cardiovascular disease in people with diabetes, Dr. Corinna Niersmann, a junior scientist at the DZD partner German Diabetes Center, was awarded the MTZ®award…

World Diabetes day on November14: diabinfo.de Expands its Offering with Additional Content

Neuherberg / Düsseldorf

Just in time for World Diabetes Day, the national diabetes information portal www.diabinfo.de has announced that it has expanded its content offering. In addition to German and Turkish, information for people with diabetes and…

DIfE Highlights at the Turn of the Decade: Biennial Report for 2019/2020 Now Available

Potsdam-Rehbrücke

How can healthy protein consumption and sustainable protein production be responsibly combined? Can micronutrients in the blood help detect frailty in elderly people at an early stage? And how do the views of others influence…

DDG Herbsttagung

DZD Spokesperson Annette Schürmann Honored with DAG Medal

Wiesbaden / Potsdam-Rehbrücke

The German Obesity Society (DAG) has awarded the DAG Medal 2021 to Professor Annette Schürmann. With this honor, the DAG recognized her many achievements in obesity research. The DAG presented the award at its annual…

Rising Star Award: Distinction for Dr. Oana-Patricia Zaharia

Düsseldorf

The clinical scientist Dr. Zaharia has investigated a new classification of diabetes into subgroups and their different risks of concomitant and secondary diseases. For these achievements and a new project on the role of adipose tissue,…

Insulin in the Brain Influences Dopamine Levels

Tübingen

In the human brain, the hormone insulin also acts on the most important neurotransmitter for the reward system, dopamine. This was shown by researchers from the German Center for Diabetes Research (DZD) in Tübingen. Insulin lowers the…

Prof. Dr. Michael Roden Named New Honorary Member of the Hungarian Diabetes Association

Düsseldorf

For his outstanding scientific achievements, Prof. Dr. Michael Roden, scientific director and executive board member of the German Diabetes Center (DDZ) and head of the Department of Endocrinology and Diabetology at Düsseldorf University…

New Issue of the DZG Magazine SYNERGIE on Precision Medicine

Berlin / Neuherberg

The right therapy for the right patient group at the right time - that is what precision medicine makes possible. In the current issue of the DZG magazine SYNERGIE, the German Centers for Health Research (DZG) show how the…

Even Without a Visit to the Doctor: New Non-Clinical Model Reliably Predicts Risk of Cardiovascular Disease

Potsdam-Rehbrücke

Up to now, a reliable risk assessment for cardiovascular diseases has required medical examinations – for example, blood pressure measurement or blood lipid analysis - and thus a visit to a doctor's office. A team led by Dr.…

Diabetes Detection with Whole-Body Magnetic Resonance Imaging

Tübingen

Type 2 diabetes can be diagnosed with a whole-body magnetic resonance imaging (MRI) scan. This is shown by a current study by researchers from the German Center for Diabetes Research, the Institute of Diabetes Research and Metabolic Diseases…

Men riding bikes by lake

New Mechanism Discovered for Improved Insulin Action Following Exercise

Düsseldorf

Regular physical activity in the form of sports is an important cornerstone of health and well-being. A new study by the German Diabetes Center has now found that targeted muscle work and the effect of the hormone insulin for people with…

Researchers overcome translational gap by developing novel in vivo model for the labeling of insulin secretory granule pools

Dresden

Pancreatic beta cells produce, store and secrete insulin upon elevated blood glucose levels. However, the highly regulated process of insulin secretion, especially its molecular features and the stimuli behind this process have not yet been…

Are Immune Cells Linked to the New Diabetes Subtypes?

Düsseldorf

With the new classification of diabetes subtypes, diabetology is on the path to precision medicine. Nevertheless, many areas remain unexplored. For example, it was previously unknown how immune cells differ in the respective subtypes. A…

DZD Annual Report Published: Targeted Promotion of Young Talent

Neuherberg

The German Center for Diabetes Research (DZD) has published its 2020 Annual Report. On 64 pages, the DZD not only presents current figures, data, and facts but also provides information about the latest developments in translational…

DIfE Inaugurates New Research Building

Potsdam-Rehbrücke

The German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE) inaugurated its new research building with a festive ceremony today. On this occasion, Dr. Birgit Schröder-Smeibidl, Administrative Director of DIfE, welcomed Dr.…

Diabetes among U.S. Children and Teens: Sharp Increase Predicted for 2060

Düsseldorf

A comprehensive study by the DDZ has examined the increase in type 1 and type 2 dia-betes in children and adolescents in the United States. The results show not only in-creasing numbers, but also differences in the population groups. How…

Insulin Directly Regulates the Circadian Clock in Adipose Tissue

Potsdam-Rehbrücke

Eating at the wrong time of day disrupts our circadian rhythm and increases the risk of obesity and type 2 diabetes. The team led by PD Dr. Olga Ramich of DIfE, Professor Achim Kramer and Professor Andreas F. H. Pfeiffer of Charité…

Gestational Diabetes: HbA1c Measurement Cannot Replace the Oral Glucose Tolerance Test for Diagnosis

Tübingen

The determination of the HbA1c value is not suitable for detecting gestational diabetes. This was the result of a study by the German Center for Diabetes Research (DZD) within the framework of the German Pregnancy Diabetes Study (PREG…

Revealing the Mystery Behind the Threat of Non-Alcoholic Fatty Liver Disease

Neuherberg

Researchers revealed how non-alcoholic fatty liver disease can develop into a life-threatening complication. Their discovery will accelerate the search for therapeutic solutions. The study was led by Helmholtz Zentrum München in…

Successful Evaluation of the DDZ by the Leibniz Association

Düsseldorf

Following the evaluation, the Senate of the Leibniz Association recommended the con-tinued funding of the German Diabetes Center (DDZ). The Center in Düsseldorf received a positive evaluation in recognition of its combination of basic…

New Study Reveals Heterogeneous Beta Cell Trajectories toward Type 2 Diabetes

Dresden

Type 2 diabetes (T2D) defines a cluster of complex pathological states characterized by persistent hyperglycemia, often leading to cardiovascular complications, kidney failure, retinopathy and neuropathies. Affecting more than 450 million…

AGEs Are Risk Factors for Vascular Stiffness Also in People Without Diabetes

Potsdam-Rehbrücke

Stiffened and narrowed arteries increase the risk of cardiovascular disease – the most common cause of death in Germany. A new epidemiological study by the German Center for Diabetes Research (DZD) and the German Institute of Human…

Gastrulation Research Reveals Novel Details about Embryonic Development

Neuherberg

Scientists from Helmholtz Zentrum München revise the current textbook knowledge about gastrulation, the formation of the basic body plan during embryonic development. Their study in mice has implications for cell replacement strategies and…

Obesity and Hypertension: Researchers Discover Novel Mechanisms

Neuherberg

Researchers have succeeded for the first time in demonstrating the role of hypothalamic astrocytes in obesity-related hypertension. In addition, they showed that the hormone leptin is involved in the increase of blood vessels in the…

Innovation in Drug Development: Morphinan Compounds Without Risk of Addiction

Düsseldorf

The modification of an active ingredient found in cough suppressants not only offers the chance of a new drug on the market, but also the possibility of developing morphine and other opiates without addictive potential in the future. What…

Yanislava Karusheva, MD Honored with the Sponsorship Award of the German Diabetes Association

Düsseldorf

Yanislava Karusheva, MD, research associate at the Institute of Clinical Diabetology of the German Diabetes Center is the recipient of the 2021 Sponsorship Award of the German Diabetes Association. She received the award for her…

Matthias Tschöp Receives the Ernst Jung Prize for Medicine 2021

Neuherberg

The Jung Foundation for Science and Research awards Matthias Tschöp with the Ernst Jung Prize for Medicine and honors his groundbreaking research on novel therapeutics for obesity and diabetes. The awards given by the Foundation rank among…

Werner Creutzfeldt Prize Awarded to Professor Michael Roden

Düsseldorf

For his outstanding research on the development of type 2 diabetes and the role of energy metabolism in humans, the German Diabetes Association has awarded the Werner Creutzfeldt Prize 2021 to Prof. Dr. Dr. h.c. Michael Roden, scientific…

EASD 2012 Berlin

Martin Hrabĕ de Angelis Receives the Highest Award of the German Diabetes Association

Neuherberg

The 2021 Paul Langerhans Medal goes to Professor Dr. Dr. h.c. mult. Martin Hrabĕ de Angelis. The German Diabetes Association (DDG) thus honors his outstanding achievements in research into the genetic and epigenetic determinants of…

DZD Researchers to Be Honored at the DDG Diabetes Congress

Neuherberg

During its virtual congress (May 12-15, 2021), the German Diabetes Society (DDG) will honor several scientists from the German Center for Diabetes Research (DZD). The most prestigious award of the DDG, the Paul Langerhans Medal, will be…

DZD at the Diabetes Congress: New Approaches to Precision Diabetes Therapy and Prevention

Neuherberg

Under the motto "Precision Medicine - a Journey into the Future of Diabetology", the 55th Annual Meeting of the German Diabetes Society (DDG) will take place digitally from May 12th. The German Center for Diabetes Research (DZD) is not…

Risk Factors for a Severe Course of COVID-19 in People with Diabetes

Düsseldorf

People with diabetes are at increased risk of developing a severe course of COVID-19 compared to people without diabetes. The question to be answered is whether all people with diabetes have an increased risk of severe COVID-19, or whether…

DZD Researcher Robert Wagner Honored with Prevention Award

Tübingen

Not everyone who has pre-diabetes with elevated blood glucose levels will go on to develop type 2 diabetes. Robert Wagner of the DZD partner Medical Clinic IV of Tübingen University Hospital has shown that there are six clearly definable…

Round Table on Nutrition in Type 2 Diabetes Ends Without Results

Berlin

Research at the German Center for Diabetes Research (DZD) must be further intensified and a ban on advertising for unhealthy children's food should be a binding part of the next coalition agreement.

 

Unfortunately, however, the round table of…

Children and Corona: Study Detects More Infections than Reported Cases During the Second Wave in Germany

Neuherberg

A study by Helmholtz Zentrum München concludes that during the second Corona wave, three to four times more children in Bavaria, Germany were infected with the Corona virus than reported via PCR tests. In addition, the researchers found…

Novel Diabetes Subgroups Show Differences in Biomarkers of Inflammation

Düsseldorf

Chronic inflammation is increasingly a focus of research. A recent study has now identified differences in indicators of inflammation between novel diabetes subgroups. But what does this mean for the future?

New Approach for the Development of a Drug Treatment for Obesity and the Resulting Diseases

Neuherberg

The protein Asc-1 regulates whether fat-burning beige or fat-storing white adipocytes are formed, which can have an impact on the development of metabolic diseases. This is shown by a current study of the Helmholtz Zentrum München and the…

Elric Zweck Receives Karl Oberdisse Award 2021

Düsseldorf

A new study by the German Diabetes Center shows that type 2 diabetes affects the energy metabolism in the human heart muscle. For this study, this year's Karl Oberdisse Award was presented to the scientist Elric Zweck.

Matthias Tschöp Receives Berthold Medal for Scientific Excellence

Neuherberg

This year’s Berthold Medal, the highest recognition of the German Society of Endocrinology (DGE), goes to Professor Matthias Tschöp, who is CEO of Helmholtz Zentrum München and Alexander-von-Humboldt Professor at Technical University of…

Hans Adolf Krebs Prize Awarded to Yanislava Karusheva, MD

Düsseldorf

The Hans Adolf Krebs Prize was awarded for the 13th time by the German Nutrition Society. This year's prize winner is Yanislava Karusheva, MD, for her study on the influence of branched-chain amino acids on glucose metabolism in type 2…

Maximilian Kleinert Heads New Junior Research Group "Muscle Physiology and Metabolism" at DIfE

Potsdam-Rehbrücke

Young scientist Dr. Maximilian Kleinert joined the German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE) at the beginning of the year. Over the next five years, he and his team will investigate the molecular signaling…

New Targets for the Development of a Drug Treatment for Obesity and Type 2 Diabetes

Neuherberg

The GIP receptor in the central nervous system plays a crucial role in the regulation of body weight and food intake. This is shown by a recent study by Helmholtz Zentrum München, ETH Zurich and the German Center for Diabetes Research…

Prediabetes: New Insights into Subtypes Pave the Way for Individual Prevention

Berlin

Type 2 diabetes is not a disease that develops suddenly. Rather, it usually develops over a period of years from a preliminary stage known as prediabetes. Even if those affected are unaware that they have prediabetes and their blood glucose…

PD Dr. Julia Szendrödi Appointed W3 Professor at the University of Heidelberg

Düsseldorf

For the past seven years, DZD scientist PD Dr. Julia Szendrödi has headed the Clinical Study Center at the German Diabetes Center. Now she has accepted a professorship at the University of Heidelberg to take over as Medical Director of the…

Scientists Discover a Promising New Target for Diabetes Treatment

Neuherberg

Researchers have discovered a novel and druggable insulin inhibitory receptor, named inceptor. The latest study from Helmholtz Zentrum München, the Technical University of Munich and the German Center for Diabetes Research is a significant…

Type 2 Diabetes: New Evidence Underlines the Role of Obesity in Late Complications

Potsdam-Rehbrücke

Successful weight loss is considered to be an integral part of the therapy for type 2 diabetes. Nevertheless, studies keep appearing that question the importance of losing weight. However, new data from a large-scale observational…

New Study Reveals Link Between Air Pollutants, Obesity and Neuropathy

Düsseldorf

In recent years, air pollutants have been suggested as risk factors for diabetes and its – also mostly obesity-associated – comorbidities. Until now, however, this link has not been investigated for peripheral neuropathy. A new study by…

Uncovering Basic Mechanisms of Intestinal Stem Cell Self-Renewal and Differentiation Promises New Approaches to Treat Diseases

Neuherberg

The gut plays a central role in the regulation of the body’s metabolism and its dysfunction is associated with a variety of diseases, such as obesity, diabetes, colitis and colorectal cancer that affect millions of people worldwide.…

Prediabetes Subtypes Identified

Tübingen

All prediabetes is not the same: in people in the preliminary stages of type 2 diabetes, there are six clearly distinguishable subtypes, which differ in the development of the disease, diabetes risk, and the development of secondary…

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