How a protein promotes the healing of inflammation
Dresden
Inflammatory processes are a natural defense reaction of the immune system against pathogens. If they get out of control, they can however lead to diseases themselves. The protein DEL-1, is a central actor that ensures that excessive…
Association of Area Deprivation and Regional Disparities in the Treatment of Children and Adolescents with Type 1 Diabetes
Neuherberg
How the autoimmune disease type 1 diabetes is treated also depends on where the patients live in Germany. In socio-economically weaker regions, insulin pumps and long-acting insulin analogs are used less frequently. Here the patients have…
The digestive system of our body is already activated before we take the first bite. Scientists from the Max Planck Institute for Metabolism Research in Cologne show how sensing food activates neurons in the brain which prime the liver for…
World Diabetes Day 2018: 6 Facts to Know about Diabetes
Neuherberg
In Germany, more people die of diabetes and its sequelae than previously thought. Being slim does not automatically mean protection against diabetes. You can determine your diabetes risk with a simple test. This and other important…
Eating Breakfast Regularly Mitigates the Risk of Type 2 Diabetes
Düsseldorf
Eat or skip breakfast? Does eating breakfast regularly mitigate the risk of diabetes? - These questions have not yet been answered conclusively by research. Around 20% of the German population skips breakfast in the morning. In the 18-29…
Professor Michael Roden Receives the 2018 Morgagni Gold Medal
Düsseldorf
Professor Michael Roden, board member of the German Diabetes Center (DDZ) – Leibniz Center for Diabetes Research, director of the Department of Endocrinology and Diabetology at Düsseldorf University Hospital and board member of the German…
New Marker Provides Insights into the Development of Type 2 Diabetes
Potsdam-Rehbrücke
Small chemical changes in the DNA building blocks, which may be influenceable by lifestyle factors, can reduce the amount of IGFBP2. A DIfE / DZD research team has now reported in the journal Diabetes that these epigenetic changes…
Awareness Campaign for Early Detection of Diabetes: Düsseldorf Active in World Diabetes Day on November 14th
Düsseldorf
Early detection of diabetes: Get involved in Düsseldorf Diabetes Week 2018! The aim of Düsseldorf Diabetes Week 2018 from November 12-18 is to raise awareness in the Düsseldorf population about diabetes mellitus and diabetes care and…
DZD Researcher Norbert Stefan Appointed Visiting Professor at Harvard Medical School
Tübingen
Professor Norbert Stefan, MD, Heisenberg Professor for Clinical Experimental Diabetology at the University of Tübingen and researcher at the German Center for Diabetes Research (DZD), was awarded a visiting professorship at Harvard Medical…
A new combined therapy for obesity and diabetes has been shown to suppress the appetite and at the same time increase energy expenditure. Scientists from the Helmholtz Zentrum München and the Technical University of Munich (TUM), partner…
Children who have a first-degree relative with type 1 or gestational diabetes can also improve their insulin sensitivity through exercise, meaning that exercise is an effective preventive strategy not only for children at risk of…
Many overweight people lack the feeling of being full. It was long thought that this was due to the disrupted transport of the satiety hormone leptin to the brain. That is not the case, as a group of scientists from Helmholtz Zentrum…
The liver is one of the few human organs that completely regenerates within a few weeks after more than half of the organ has been removed. However, so far the cause of this remarkable feature remains unclear. Within the framework of the…
DZD at EASD: Presentation of Achievements in Translational Research
Neuherberg
Information on translational diabetes research, presentation of current research results, meetings between young scientists and people with diabetes – that and much more will be offered by the German Center for Diabetes Research (DZD) at…
The Curse of the Sugar Cube: Professor Blitz Delights around 300 Pupils with Magic Nutrition Tricks
Düsseldorf
The children stare at the magician Professor Blitz in disbelief, then the applause erupts. The magician has just conjured up a large sugar cube into a food package with the help of a confetti cannon. The magician playfully explains to the…
Young Investigator Workshop in Bioanalytics: Basic Lab Techniques and Latest Methods
Düsseldorf
Chemists, molecular biologists and physicians learned about the latest methods in the field of bioanalytics at the German Diabetes Center (DDZ), a partner of the German Center for Diabetes Research (DZD). At the one-week Rainbow Workshop…
Extensive insights into metabolism – the orchestra in the body
Neuherberg
A recent paper published in the scientific journal Cell gives an unprecedented insight into the metabolic interactions that occur throughout the body over 24 hours. As part of a large-scale study, the authors constructed 24-hour metabolic…
Novel Concepts for the Diagnosis of Fatty Liver and Personalized Treatment: A Review and Recommendations
Tübingen
Almost one in three adults in industrialized countries suffer from non-alcoholic fatty liver. For the affected people this increases the risk of complications such as liver cirrhosis, liver cancer, type 2 diabetes, high blood pressure, heart…
A plant-derived substance widely used in traditional Chinese medicine has demonstrated promising weight loss effects. The findings of a study conducted by scientists at the Helmholtz Zentrum München, a partner of the German Center for…
Numb, Burning and Tingling Sensations in the Feet: New Biomarkers of Inflammation Identified as Risk Factors for Neuropathy
Düsseldorf
Polyneuropathy is one of the most common complications in people with diabetes. However, it can also occur with certain risk factors or diseases before the onset of diabetes. First symptoms are often pins-and-needles sensations in the…
How do muscle cells prepare for the particular metabolic challenges of the day? Scientists at Helmholtz Zentrum München and Ludwig-Maximilians-Universität München (LMU), members of the German Center for Diabetes Research (DZD), have…
Matthias Tschöp appointed new CEO of Helmholtz Zentrum München
Neuherberg
Professor Matthias Tschöp, MD, has been appointed the new CEO of Helmholtz Zentrum München. He took over from Professor Günther Wess, who led the center for the past 13 years, on August 1, 2018.
Interdisciplinary Conference: Globally leading experts in Diabetes, Metabolism and Biomedical Engineering meet to discuss future concepts for Precision Medicine
Neuherberg
New technologies enable deeper insights into the causes of major diseases such as diabetes, obesity or cancer and open the way to a new generation of diagnostics and therapies. For the first time, the new Helmholtz Pioneer Campus (HPC) at…
High Prevalence of Restrictive Lung Disease in People with Type 2 Diabetes
Heidelberg
Breathlessness and conditions of restrictive lung disease (RLD), such as pulmonary fibrosis, may be a late complication of type 2 diabetes. These are the key findings of a joint study undertaken by researchers from the German Center for…
The Mediterranean Diet Is Healthy – Even Far Away from Mediterranean Regions
Potsdam-Rehbrücke
New analyses of the EPIC-Potsdam study show that a Mediterranean diet can reduce the risk of type 2 diabetes even outside the Mediterranean region. In addition, a diet consisting of vegetables, fruits, olive oil and the like may…
Specific Liver Fats: Warning Signs of Fatty Liver Disease and Insulin Resistance
Düsseldorf
Overweight and type 2 diabetes are associated with nonalcoholic fatty liver disease (NAFLD). Worldwide, about 50 to 75 percent of people with type 2 diabetes have fatty liver. 10 to 20 percent of these patients even suffer from liver…
With the Aqua Trampoline, the Düsseldorf municipal swimming pool company offers the children participating in the SMS initiative a fun exercise session in the water.
Heart Attack and Stroke Risk Also Elevated in Women with Obesity Who Are Metabolically Healthy
Potsdam-Rehbrücke
Women with obesity are at increased risk of cardiovascular disease, even if they are considered to be metabolically healthy. Moreover, women of normal weight are at risk of heart attack or stroke if they suffer from a metabolic…
Abdominal Fat Secretes Novel Adipokine Promoting Insulin Resistance and Inflammation
Neuherberg
An international research team in which the DZD is participating has identified a novel adipokine that favors the development of insulin resistance and systemic inflammation. In cases of severe obesity, this adipokine is secreted by the…
DZD Researcher Tim Schulz Awarded Paul Ehrlich and Ludwig Darmstaedter Prize for Young Researchers
Neuherberg
The 2018 Paul Ehrlich and Ludwig Darmstaedter Prize for Young Researchers will be awarded today to Professor Tim Schulz in recognition of his biomedical research on the function of brown and white adipocytes (fat cells). At the German…
As we are approaching the 100th anniversary of the discovery of insulin, a wide array of its signaling pathways has been defined. However, the initial step in insulin action, i.e. the engagement with its cell-surface receptor and the…
Type 2 Diabetes: the Costs of Treating Complications
Neuherberg
Scientists at the Helmholtz Zentrum München have examined health insurance data of more than 300,000 people with diabetes in Germany. Their report, published in the medical journal ‘Diabetes Care’, breaks down the costs involved in…
Prostate Cancer: Poor Prognosis in Men with Diabetes
Tübingen/Neuherberg
Men with type 2 diabetes are less likely to develop prostate cancer than patients without diabetes. However, the mortality rate is higher. Researchers of the German Center for Diabetes Research (DZD) from Tübingen and experts of…
Scientists have identified a network of genes that could play an important role in the development of metabolic diseases such as diabetes. A research team from the Helmholtz Center Munich and the International Mouse Phenotyping Consortium…
Maren Carstensen-Kirberg Receives Award from Dr. Eickelberg Foundation for Biomarker Research
Düsseldorf
Dr. Maren Carstensen-Kirberg, research associate at the German Diabetes Center (DDZ), has been awarded the Dr. Eickelberg Foundation Prize 2017 for her research into biomarkers. An interdisciplinary team received the project grant for…
Autoimmune Reaction Successfully Halted in Early Stage Islet Autoimmunity
Neuherberg
Scientists at Helmholtz Zentrum München have discovered a mechanism that amplifies the autoimmune reaction in an early stage of pancreatic islet autoimmunity prior to the progression to clinical type 1 diabetes. If the researchers blocked…
