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Recent research underscores the critical role of adipocytes in storing fat, vital for organismal survival. Dysfunctional adipocytes can lead to metabolic disorders like type 2 diabetes and fatty liver disease, highlighting the importance of understanding lipid storage mechanisms. A team of scientists led by DZD partner Helmholtz Munich have developed a novel approach merging proteomics with machine learning to map dynamic changes during adipogenesis.

Human adipocyte with lipid droplet labeled in magenta and regulatory protein in green. © Helmholtz Munich, Felix Klingelhuber

This method reveals new insights into protein regulation, offering potential targets for managing metabolic diseases.

Detailed information in our press release

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Role of Adipocytes in Metabolic Disorders Recognized