German Diabetes Study (GDS)
This study is investigating how an existing diabetes mellitus develops in the long term after diagnosis.
Background of the Study
The German Diabetes Study observes patients with newly diagnosed type 1 or type 2 diabetes for a period of 10 years. Thus, early warning signs for later complications can be discovered, and all approved therapy procedures can be compared in parallel. The study also investigates the influence of heredity (genes) on disease progression.
The study is being conducted at seven locations within the framework of the German Center for Diabetes Research (DZD) in Germany.
- Men and women between 18 and 69 years of age
- With type 1 or type 2 diabetes; diagnosis made not more than 1 year prior to enrollment in the study or healthy control participants without diabetes
- All treatment forms allowed (dietary, pills, injections, insulin therapy)
Most Important Exclusion Criteria
- Age under 18 or over 69 years
- Certain endocrine diseases/disorders of the hormone system
- Chronic gastrointestinal diseases
- Mental illness, addiction
- Anti-inflammatory or immunosuppressive therapy
- Acute or chronic infectious diseases
- Malignant tumor diseases (cancer)
- Certain liver and gallbladder diseases
- Kidney failure
- Particular coagulation disorders
Course of the Study
At the start of the study, and after 5 and 10 years, several days of examinations take place. These include different metabolic tests, if necessary the taking of blood samples and adipose tissue samples, several examinations of the nervous system and the cardiovascular system, and a magnetic resonance tomography of the liver (MRI).
In between you will be contacted once a year to track the progress of your disease.
There is NO additional medication within the framework of the clinical study. The study ends after a total of 10 years.
- Physical examination by a doctor
- Body measurements (weight, height, hip and waist circumference)
- Blood samples
- Metabolic tests (measurement of remaining endogenous insulin secretion and insulin sensitivity using various laboratory methods)
- Examination of the nervous system (variability of the pulse rate, neuropathy tests)
- Examination of the cardiovascular system (measurement of blood pressure, blood vessel tests, ECG)
- MRI (magnetic resonance imaging of intra-abdominal fat and liver fat content)
Compensation for Expenses
All examinations are free of charge for you. The costs are borne by the Center. Please inquire about a financial compensation at the respective study center.
Prof. Dr. Michael Roden
German Diabetes Center
Prof. Dr. Andreas Fritsche, Prof. Dr. Norbert Stefan,
Tübingen University Hospital
Prof. Dr. Andreas Pfeiffer
German Institute of Human Nutrition /
Phone: 033200–882778 oder 882774
Prof. Dr. Jochen Seißler,
PD Dr. Andreas Lechner
Prof. Dr. Julia Szendrödi
Heidelberg University Hospital
Phone: 06221 56-8606
Dr. Sabine Fischer
Dresden University Hospital
Phone: 0351 4583701
Prof. Sebastian Schmid
Schleswig-Holstein University Hospital
Phone: 0451 3101 7864